Fact Sheet: President Donald J. Trump Unveils the Genesis Mission
to Accelerate AI for Scientific Discovery
USHERING IN A NEW ERA OF DISCOVERY: Today, President Donald J. Trump signed an Executive Order launching the Genesis Mission, a new national effort to use artificial intelligence (AI) to transform how scientific research is conducted and accelerate the speed of scientific discovery.
- The Genesis Mission charges the Secretary of Energy with leveraging our National Laboratories to unite America’s brightest minds, most powerful computers, and vast scientific data into one cooperative system for research.
- The Order directs the Department of Energy to create a closed-loop AI experimentation platform that integrates our Nation’s world-class supercomputers and unique data assets to generate scientific foundation models and power robotic laboratories.
- The Order instructs the Assistant to the President for Science and Technology (APST) to coordinate the national initiative and the integration of data and infrastructure from across the Federal government.
- The Secretary of Energy, APST, and the Special Advisor for AI & Crypto will collaborate with academia and private-sector innovators to support and enhance the Genesis Mission.
- Priority areas of focus include the greatest scientific challenges of our time that can dramatically improve our Nation’s national, economic, and health security, including biotechnology, critical materials, nuclear fission and fusion energy, space exploration, quantum information science, and semiconductors and microelectronics.
HARNESSING AI FOR OUR NATIONAL SECURITY AND ECONOMIC DEVELOPMENT: With the Genesis Mission, the Trump Administration intends to dramatically expand the productivity and impact of Federal research and development within a decade.
- Despite research budgets soaring since the 1990s, scientific progress has stalled—new drug approvals have declined, and more researchers are needed to achieve the same outputs.
- Harnessing AI as a scientific tool will revolutionize the way scientific research is conducted.
- For example, AI technologies can generate models of protein structures and novel materials, design and analyze experiments, and aggregate and generate new data faster and more effectively. Research that once took years could now take weeks or months.
- To do this, AI needs large amounts of organized and high-quality data and significant computing power. These datasets and computing technology already exist within DOE’s National Laboratories. With the Genesis Mission, the Trump Administration is bringing the power of AI to bear on our already expansive data infrastructure and creating a platform for multiple Federal research agencies and the private sector to collaborate to achieve breakthroughs currently thought impossible, and to win and stay ahead in the AI race.
STRENGTHENING AMERICA’S AI DOMINANCE: President Trump continues to prioritize America’s global dominance in AI to usher in a new golden age of human flourishing, economic competitiveness, and national security.
- In January, President Trump signed an Executive Order to reverse harmful Biden Administration AI policies and enhance America’s global AI dominance.
- In April, President Trump signed an Executive Order to advance AI education for America’s youth.
- In July, President Trump signed Executive Orders to prevent woke AI in the Federal government and promote the export of full-stack American AI technologies.
- In July, President Trump issued America’s AI Action Plan, a policy agenda identifying nearly a hundred Federal actions to accelerate American AI innovation, build AI infrastructure at home, and lead in international diplomacy and security.
- The AI Action Plan includes recommended policies for investing in AI-enabled science, including the direction to build world-class data sets.
- In September, the President signed an Executive Order on harnessing AI innovation to unlock cures for pediatric cancer, using the Childhood Cancer Data Initiative, which President Trump initially established in 2019 to collect, generate, and analyze childhood cancer data.

