President Trump Delivers Largest Prescription Drug Price Drop in Over 60 Years
President Donald J. Trump promised to slash prescription drug prices — and he has delivered. New data confirms prescription drug prices just recorded their largest annual decline in more than 60 years, the steepest drop since 1963, as the Trump Administration’s landmark Most Favored Nation policies take hold.

President Trump is the first President to actually lower prescription drug prices — a direct result of his bold action. Through Most Favored Nation pricing, 17 of the world’s largest drugmakers — covering approximately 86% of the branded drug market — have agreed to bring U.S. prices in line with the lowest paid by comparable developed nations, ending decades of Americans subsidizing cheaper drugs abroad and forcing fair pricing for patients at home.

The Trump Administration’s revolutionary TrumpRx platform has already generated $700 million in savings for millions of American patients. GLP-1 medications that once cost over $1,000 a month are now available starting as low as $149. Fertility drugs, inhalers, insulin, cholesterol treatments, and dozens of other high-cost drugs have seen cuts of 50–90% or more.
The results are clear:
- Prescription drug prices are down 3.9% since President Trump took office and have fallen every month of 2026. Nonprescription drugs are down 2.4% over the same period.
- Medical care commodities, including equipment and supplies, are down 2.7% over the past year.
- The Department of Veterans Affairs has locked in more than $10 billion in pharmaceutical savings this fiscal year alone.
- Hundreds of billions more in long-term savings are projected from the full Most Favored Nation framework.
No previous Administration achieved this. President Trump’s Most Favored Nation policy and TrumpRx are driving the largest prescription drug price drop in over six decades — delivering real relief to American families and putting patients first.

